Discover Research Highlights

Learn about the discoveries and breakthroughs that underpin our Program and technologies.

Research Highlights

We are committed to doing our part to solve some of world’s largest challenges in the fight against neurodegeneration.

Audiovisual
Neuromodulation

Learn about the science that underpins some of our technology development.

Neurons that fire together, shower together!

Nature, Feb 2024

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Sensory stimulation helps clear protein aggregration.

Nature, Feb 2024

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40 Hz sensory stimulation protects neurons from damage.

Nature Comms, Aug 2024

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40 Hz sensory stimulation modulates the brain’s immune environment.

Science Advances, Aug 2023

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40 Hz sensory stimulation promotes sleep.

Cell Research, Feb 2024

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40 Hz audiovisual stimlation improves cognitive function.

Journal of Internal Medicine, Dec 2023

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Vibrotactile
Neuromodulation

Learn about the science that underpins some of our development of new digital technologies.

Vibrating “Emma watch” helps reduce the motor symptoms of Parkinsons.

JMIR Biomedical Engineering, Oct 2023

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Vibration from wearable is safe, well tolerated, and may attenuate tremor.

Front. Hum. Neurosci., Nov 2021

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Parkinson’s symptoms improved with vibroacoutic therapy.

MDPI Healthcare, Apr 2020

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Biomarker
Tracking

Learn about our research using smartphones and smartwatches in neurology to track biomarkers.

  • Stirling, R et al. “User experience of a seizure risk forecasting app: A mixed methods investigation”. Epilepsy & Behavior 157 (2024).

    Brinkmann, B et al. “Seizure forecasting and detection with wearable devices and subcutaneous EEG-outcomes from the my seizure gauge trial.” Epilepsia 64. (2023).

    Nasseri, M et al. “Optimized seizure forecasting with wearable devices using multi-day cycles and acute machine learning.” Epilepsia 64, (2023).

    Stirling, R et al. “Prospective validation of a mobile and wearable app to forecast seizure risk.” Epilepsia 64 (2023).

    Xiong W et al. “Forecasting seizure likelihood from cycles of self-reported events and heart rate: a prospective pilot study.” EBioMedicine. (2023).

    Stirling RE et al. “Sleep and seizure risk in epilepsy: bed and wake times are more important than sleep duration.” Brain. (2023).

    Gregg NM et al. “Seizure occurrence is linked to multiday cycles in diverse physiological signals.” Epilepsia. (2023)

    Brinkmann B, et al. “Seizure Forecasting and Detection with Wearable Devices and Subcutaneous EEG–Outcomes from the My Seizure Gauge Trial”. Neurology. (2023)

    Nasseri M et al. “Ambulatory seizure forecasting with a wrist-worn device using long-short term memory deep learning.” Nature Scientific Reports. (2021).

    Karoly PJ, et al. “Multiday cycles of heart rate are associated with seizure likelihood: An observational cohort study.” EBioMedicine. (2021).

    Stirling RE, et al. “Forecasting seizure likelihood with wearable technology.“ Frontiers in neurology. (2021).

    Brinkmann BH, et al. “Seizure diaries and forecasting with wearables: epilepsy monitoring outside the clinic.” Frontiers in Neurology. (2021).

    Nasseri M, et al. “Non-invasive wearable seizure detection using long–short-term memory networks with transfer learning.” Journal of neural engineering. (2021).

    Payne DE, et al. “Identifying seizure risk factors: A comparison of sleep, weather, and temporal features using a Bayesian forecast.” Epilepsia. (2021).

    Karoly PJ, et al. “Forecasting cycles of seizure likelihood.” Epilepsia. (2020).

    Nasseri M, et al. “Signal quality and patient experience with wearable devices for epilepsy management.” Epilepsia. 61 (2020).

    Karoly PJ, et al. Multiday cycles of heart rate modulate seizure likelihood at daily, weekly and monthly.“ Psychiatry. (2018).

PKG, a world-first Aussie innovation.

Journal of Parkinson’s Disease, 2012

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Digital health technologies are more accurate for tracking disease progression.

Communications Medicine, 2024

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A highly cited review on wearables in Parkinons’s Disease.

Frontiers in Neuroscience, 2017

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Real world data deepens our understanding of Parkinson’s disease.

NPJ Parkinson’s Disease, 2021

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Exercise

Examples of research that has inspired our team. The evidence presented in these publications showing the impact of exercise on fighting neurodegneration is absolutely mind-blowing!

High intensity exercise prevents neurodegeneration.

NPJ Parkinson’s Disease, Feb 2024

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Excersise delays the need to have more medications!

Rehab in Parkinson’s Disease, Feb 2022

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Tango is a potent intervention for slowing neurodegernation.

J Rehabil Med, May 2009

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Sleep

The evidence is in. Sleep optimisation is a potent intervention for fighting neurodegeneration. Here is some research that has inspired our team.

Sleep Drives Metabolite Clearance from the Adult Brain.

Science, Oct 2013 (an oldie but a goodie)

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Sleeping Your Mind Clear.

Arch. of Mol. Bio. and Gen., Mar 2022

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Sleep Deprivation Interferes with Waste Clearance.

Brain Comms, Dec 2023

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Nutrition

Nutrition research that has inspired our team

What is the MIND Diet?

An overview.

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The MIND diet can slow the progrssion of Parkinson’s.

Nutrition, health & aging, Dec 2018

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The MIND Diet and Alzheimer’s.

Alzheimers Dement., Sept 2015

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